Despite the heightened hardship and uncertainty that characterized 2020, the year ended with cautious optimism, following the worldwide launch of a COVID-19 vaccination campaign. In the occupied Palestinian territory (oPt), this campaign is yet to start; however, the Palestinian Authority (PA) has applied for financial support and has developed a national plan aimed at mass vaccination in the near future. Israel began vaccination in mid-December, and currently ranks first globally in per capita coverage. The Israeli authorities have expressed their readiness to support vaccinations both in the West Bank and in Gaza, however practical arrangements are yet to come to fruition. Health and human rights organizations have called on the Israeli authorities to “live up to their legal obligations and ensure that quality vaccines” are also provided to Palestinians.