The Humanitarian Response Plan (HRP) for the occupied Palestinian territory (oPt) is part of the 2016 Global Humanitarian Overview, which is requesting a record US$20.1 billion to fund humanitarian operations around the world this year. The oPt HRP was launched locally in February and plans to support one in three Palestinians with some form of humanitarian assistance in 2016. It includes 206 projects worth $571 million, 19 per cent less than the sum requested in 2015. Seventy-nine organizations are participating: 12 UN agencies, 36 international NGOs and 31 national NGOs. Approximately one third of funds requested are designated as “top priority” to help guide where limited resources should be allocated first. Although the oPt HRP shares many of the features of other operations around the world, the context of the oPt is unique - a protracted protection crisis that stems from the impact of a military occupation approaching its 50th anniversary. Gender has been mainstreamed throughout all HRP objectives and all cluster strategies to ensure the protection of all members of the affected population and to guarantee effective and equitable delivery of humanitarian assistance.